Table 2.
TPE in patients with autoimmune encephalitis (AE).
| n | Age | Gender | Details | Antibody | Memo | Epil | Psych | Move | Auto | Sleep | Pons | Detection of Lesion on MRI | CSF | Treatment | TPE Courses | Clinical Response |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 42 | M | Paraneopl.AE | Ma1/Ma2 | + | + | + | + | temporomesial | neg. | TPE/OP/Ritux | 3 | no | |||
| 2 | 29 | W | NMDAR-E | NMDAR | + | + | + | diffuse | IgG ↑ | TPE/IVIG | 10 | good | ||||
| 3 | 26 | W | NMDAR-E | NMDAR | + | + | none | 33 cells | TPE/IVIG/OP | 5 | good | |||||
| 4 | 30 | W | NMDAR-E | NMDAR | + | + | none | neg. | TPE/IVIG/OP | 5 | good | |||||
| 5 | 25 | F | NMDAR-E | NMDAR | + | + | + | none | 10 cells | TPE/IVIG/GC/OP | 13 | no | ||||
| 6 | 64 | M | LE | LGI-1/VGKC | + | + | + | temporomesial | 9 cells | TPE/IVIG/GC | 5 | mild | ||||
| 7 | 55 | M | LE | none | + | temporomesial | 21 cells | TPE/IVIG | 5 | mild | ||||||
| 8 | 62 | M | LE | AMPA-R1 | + | + | temporomesial | 16 cells | TPE/IVIG/Ritux | 7 | no | |||||
| 9 | 66 | M | LE | LGI-1 | + | + | none | neg. | TPE/ IVIG/ GC | 4 | good | |||||
| 10 | 24 | F | probable LE | none | + | + | + | temperomesial | neg. | TPE/IVIG/GC | 5 | mild | ||||
| 11 | 71 | M | Brainstem E | none | + | pons | neg. | TPE/IVIG | 7 | good | ||||||
| 12 | 47 | M | Brainstem E | none | + | pons | neg. | TPE/IVIG/GC | 6 | mild |
Legends: LE: Limbic Encephalitis; NMDAR-E: NMDAR-Encephalitis; Brainstem E: Brainstem Encephalitis; memo: memory-deficit; epi: epileptic seizure; psych: psychiatric disorders; move: movement disorders; auto: autonomic dysfunction; sleep: sleep disturbance; pons: pontine signs; IVIG: intravenous immunoglobulins; GC: Glucocorticoids; OP: tumor surgery; Ritux: Rituximab.