Table 1.
Variables affecting 5-year DFS in the mRNA microarray cohort [18].
| Variables | Univariate Cox Analysis | Multivariate Cox Analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
| Gender (male vs. female) | 1.254 | 0.885–1.777 | 0.202 | |||
| Age | 1.009 | 0.995–1.023 | 0.199 | |||
| Staging (III vs. II) | 1.958 | 1.388–2.764 | <0.0001 | 1.836 | 1.221–3.761 | 0.003 |
| Chemotherapy (yes vs. no) | 1.526 | 1.085–2.146 | 0.015 | 1.096 | 0.732–1.641 | 0.658 |
| Location (proximal vs. distal) | 0.877 | 0.618–1.246 | 0.464 | |||
| SPARC (high vs. low) | 1.410 | 1.001–1.989 | 0.050 | 1.408 | 0.998–1.985 | 0.051 |
Variables affecting DFS were first analyzed in a univariate model. Those variables that had a statistically significant impact were then used in a multivariate Cox regression model. Significant variables are written in bold. DFS = disease-free survival; HR = hazard ratio; CI = confidence interval.