Table 2.
Variables affecting 5-year OS in patients of the tissue microarray cohort with recurrent disease.
| Variables | Univariate Cox Analysis | Multivariate Cox Analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
| Gender (male vs. female) | 2.256 | 0.800–6.366 | 0.124 | |||
| Age | 1.052 | 1.001–1.105 | 0.045 | 1.053 | 0.999–1.109 | 0.055 |
| Staging (III vs. II) | 1.907 | 0.550–6.608 | 0.309 | |||
| Chemotherapy (yes vs. no) | 0.744 | 0.263–2.107 | 0.578 | |||
| Location (proximal vs. distal) | 2.362 | 0.932–5.992 | 0.070 | 0.338 | 0.123–0.931 | 0.036 |
| SPARC (high vs. low) | 3.607 | 1.337–9.732 | 0.011 | 4.574 | 1.609–13.004 | 0.004 |
Variables affecting OS were first analyzed in a univariate model. Those variables that had a statistically significant impact were then analyzed together using multivariate Cox regression. Variables found to be significant are written in bold. OS = overall survival; HR = hazard ratio; CI = confidence interval.