Figure 2.

Changes in neuronal activity with cooling in rat brain slices. (a) Representative examples of action potentials induced by current injections in rat brain slices for the cooling condition. Traces show each series of current injections performed before (precooling) during (cooling) and after cooling (recovery). (b) Mean resting membrane potential, firing threshold, and spike duration. Note that all these parameters recovered to the precooling levels. The number of neurons is shown at the base of each bar. (c) Mean input/output relationship during precooling (filled), cooling (blue), and recovery from cooling (open). *P < 0.05 vs. precooling. Error bars indicate ± SEM.