Table 2.
Effect of increase in naringenin concentration on particle size, polydispersity index, zeta potential, and entrapment efficiency.
| Formulation Code | Concentration of NAR (mg/mL) | PS ± SD (nm) | PDI ± SD | ZP ± SD (mV) | %EE ± SD |
|---|---|---|---|---|---|
| F1N1 | 0.1 | 72.7 ± 4.95 | 0.29 ± 0.02 | 19.66 ± 2.53 | 84.85 ± 5.25 |
| F1N2 | 0.25 | 87.6 ± 8.47 | 0.31 ± 0.04 | 15.36 ± 2.05 | 91.12 ± 2.99 |
| F1N3 | 0.50 | 385.1 ± 16.4 | 0.59 ± 0.05 | 12.53 ± 0.73 | 74.6 ± 4.09 |
| F1N4 | 1.0 | 857.7 ± 23.6 | 0.68 ± 0.06 | 18.8 ± 0.70 | 59.1 ± 5.32 |
Formulation code F1N1 to F1N4 consist of fixed chitosan concentration (0.5 mg/mL); TPP volume 4 mL, stirring speed 600 rpm; stirring time 30 min. EE: entrapment efficiency; NAR: Naringenin. Values are expressed as mean ± SD (n = 3), three independent experiments performed in triplicate.