Table 3.
Univariate Cox regression analysis of OS on the six immune subtype clusters described in Thorsson et al. [17]
| Cluster | Status | Number of Samples | HR | 95% CI for HR | p Value |
|---|---|---|---|---|---|
| Cluster 1 | TMB/TGF- score positive | n = 2200 | 0.82 | 0.64–1 | 0.11 |
| Cluster 2 | TMB/TGF- score positive | n = 2357 | 0.76 | 0.61–0.93 | 0.0095 |
| Cluster 3 | TMB/TGF- score positive | n = 1867 | 0.84 | 0.53–1.3 | 0.48 |
| Cluster 4 | TMB/TGF- score positive | n = 1061 | 0.72 | 0.52–0.99 | 0.044 |
| Cluster 5 | TMB/TGF- score positive | n = 368 | 1.7 | 0.71–3.9 | 0.24 |
| Cluster 6 | TMB/TGF- score positive | n = 154 | 2.7 | 1.1–6.8 | 0.037 |
Abbreviations: OS, overall survival; HR, hazard ratio; CI, confidence interval.