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. 2019 Nov 4;11:54. doi: 10.1186/s13099-019-0336-3

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Genetic characteristics of PaLoc in Clostridioides difficile strain B18-123. (a) Comparative genomic structure analysis of PaLoc among C. difficile strains used in this study. (b) Phylogenetic tree of PaLoc among 12 strains deposited in the GenBank by maximum likelihood method based on Tamura-Nei model [24] using MEGA X software [25]. Strains surrounded by dotted line belong to ST67. (c) tcdC sequence alignment for C. difficile strains used in this study. Identical nucleotides among their strains are indicated with an asterisk. (d) Phylogenetic tree of tcdC sequences among 12 strains deposited in the GenBank by maximum likelihood method based on Tamura-Nei model [24] using MEGA X software [25]. Strains indicated with an asterisk belong to ST67