Table 3.
Weight changes of rats before and after the treatments in different groups. Normal, normal rats received distilled water (5 mL/kg/day); control, rats with colitis received distilled water (5 mL/kg/day). Data are expressed as mean ± SD, n = 6. T-paired test was used for data analysis.
| Group (dose, mg/kg/day) | Weight variation (g) | P value | |
|---|---|---|---|
| Before | After | ||
| Normal | 192.0 ± 2.9 | 203.8 ± 1.9 | < 0.001 |
| Control | 206.2 ± 7.3 | 192.1 ± 7.2 | < 0.01 |
| GAL (0.25) | 181.3 ± 11.6 | 184.8 ± 11.3 | NS |
| GAL (1.25) | 202.2 ± 7.7 | 198.5 ± 7.3 | NS |
| GAL (2.5) | 196.0 ± 8.6 | 187.8 ± 8.6 | NS |
| DIC (5) + GAL (0.25) | 180.2 ± 0.7 | 183.3 ± 0.7 | NS |
| DIC (5) + GAL (1.25) | 219.2 ±2.2 | 218.8 ± 1.8 | NS |
| DIC (5) + GAL (2.5) | 205.5±0.9 | 201.3±0.7 | NS |
| DIC (5) | 183.3 ± 3.7 | 189.2 ± 4.8 | NS |
| Prednisolone (4) | 205.0 ± 4.9 | 215.7 ± 2.0 | < 0.01 |
| Mesalazine (100) | 211.5 ± 5.1 | 220.3 ± 7.6 | < 0.05 |
GAL, galantamine; DIC, dicyclomine; NS, non-significant.