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. 2019 Nov 4;16:203. doi: 10.1186/s12974-019-1583-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — a Electron microscopy images of longitudinal sections of the optic nerve fibers from sham- and MOG_35–55-treated C57Bl/6J wild-type mice. b The myelin-axon ratio was determined by the thickness of the myelin sheath and the axon. Bar graphs represent the pooled mean ± SD of an EAE experiment with four animals per group; **P < 0.01 two-tailed Student’s t test compared to sham-treated mice