Table 2.
Effect of patient- and clinical determinants on door-to-needle time, expressed in odds ratio’s (with 95th confidence intervals) for different cut-off points
| Door-to-needle time | |||||
|---|---|---|---|---|---|
| Univariate analysis | Multivariable analysis | ||||
| Cut-off point in minutes | Median | 90th percentile | Mediana | 90th percentileb | |
| 26 | 55 | 26 | 55 | ||
| Age (years) | |||||
| < 50 | 1.19 (1.01–1.40)c | 1.42 (1.11–1.81) c | 1.16 (0.98–1.37) | 1.38 (1.07–1.76) d | |
| 50–75 | Reference | ||||
| > 75 | 1.12 (0.98–1.27) | 1.18 (0.95–1.45) | 1.11 (0.97–1.27) | 1.21 (0.97–1.49) | |
| Female sex | 1.21 (1.11–1.32) c | 1.08 (0.94–1.24) | 1.17 (1.05–1.31)d | – | |
| Onset-to-door time (minutes) | |||||
| < 40 | 1.10 (0.99–1.23) | 1.42 (1.20–1.66) c | 1.15 (1.00–1.33) | 1.37 (1.11–1.69) d | |
| 40–180 | Reference | ||||
| > 180 | 0.76 (0.65–0.88) c | 0.40 (0.28–0.57) c | 0.75 (0.61–0.91) d | 0.46 (0.28–0.56) d | |
| Admission to comprehensive stroke center | 0.94 (0.86–1.03) | 1.27 (1.10–1.46) c | – | 1.26 (1.04–1.50) d | |
| Admission during off-hours | 1.15 (1.06–1.25) c | 1.08 (0.95–1.24) | 1.12 (1.01–1.25) d | – | |
| Year of inclusion | |||||
| 2015 | 1.24 (1.14–1.34) c | 0.97 (0.85–1.11) | 1.33 (1.14–1.35) d | – | |
| 2016 | Reference | ||||
aAdjusted for age, female sex, onset-to-door time, admission during off-hours and year of inclusion. bAdjusted for age, onset-to-door time and admission to comprehensive stroke center. cP-value below 0.1. dP-value below 0.05