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. 2019 Nov 4;19:265. doi: 10.1186/s12883-019-1512-2

Table 4.

Effect of patient and clinical factors on in-hospital mortality

In-hospital mortality
Univariate analysis Multivariable analysis
OR(95%CI) p-value OR (95% CI) p-value
Age (years)
< 50 0.18 (0.06–0.43) < 0.01 0.17 (0.05–0.41) < 0.01
50–75 Reference
> 75 3.53 (2.90–4.31) < 0.01 3.45 (2.86–4.19) < 0.01
Female sex 1.33 (1.12–1.58) < 0.01 1.06 (0.89–1.27) 0.51
Admission to comprehensive stroke center 1.32 (1.10–1.57) < 0.01 1.39 (1.56–1.66) < 0.01
Admission during off-hours 1.09 (0.92–1.29) 0.34
Year of inclusion
2015 0.91 (0.77–1.08) 0.27
2016 Reference
Onset-to-door time
< 180 Reference
> = 180 0.88 (0.63–1.19) 0.42
Door-to-needle time
< 55 Reference
> = 55a 1.48 (1.15–1.88) < 0.01 1.54 (1.19–1.98) < 0.01

aCorresponding with the 90th percentile