Table 1.
DAVID functional analysis of upregulated proteins at global level at 3 h after the blast and proteins enriched in each category
| Categories | GO Terms | ACCESSION | GENE NAME |
|---|---|---|---|
| BP | Positive regulation of filopodium assembly | ||
| Q99JY9 | ARP3 actin-related protein 3(Actr3) | ||
| Q62188 | Dihydropyrimidinase-like 3(Dpysl3) | ||
| Q61553 | Fascin actin-bundling protein 1(Fscn1) | ||
| P35802 | Glycoprotein m6a(Gpm6a) | ||
| Actin filament organization | |||
| Q99JY9 | ARP3 actin-related protein 3(Actr3) | ||
| Q641P0 | ARP3 actin-related protein 3B(Actr3b) | ||
| Q9QXS6 | Drebrin 1(Dbn1) | ||
| Q61553 | Fascin actin-bundling protein 1(Fscn1) | ||
| Q60875 | Rho/rac guanine nucleotide exchange factor (GEF) 2(Arhgef2) | ||
| Learning | |||
| O88587 | Catechol-O-methyltransferase(Comt) | ||
| O35927 | Catenin (cadherin associated protein), delta 2(Ctnnd2) | ||
| P42859 | Huntingtin(Htt) | ||
| P31324 | Protein kinase, cAMP dependent regulatory, type II beta(Prkar2b) | ||
| Axon guidance | |||
| P97427 | Collapsin response mediator protein 1(Crmp1) | ||
| Q9EQF6 | Dihydropyrimidinase-like 5(Dpys15) | ||
| O08917 | Flotillin 1(Flot1) | ||
| P06837 | Growth associated protein 43(Gap43) | ||
| P13595 | Neural cell adhesion molecule 1(Ncam1) | ||
| Positive regulation of axon extension | |||
| Q9QXS6 | Drebrin 1(Dbn1) | ||
| P10637 | Microtubule-associated protein tau(Mapt) | ||
| Q9D8E6 | Ribosomal protein L4(Rpl4) | ||
| Microtubule-based process | |||
| P63168 | Dynein light chain LC8-type 1(Dynll1) | ||
| P68369 | Tubulin, alpha 1A(Tuba1a) | ||
| Q7TMM9 | Tubulin, beta 2A class IIA(Tubb2a) | ||
| Regulation of synaptic plasticity | |||
| O35927 | Catenin (cadherin associated protein), delta 2(Ctnnd2) | ||
| P42859 | Huntingtin(Htt) | ||
| P13595 | Neural cell adhesion molecule 1(Ncam1) | ||
| CC | Axon | ||
| P63054 | Purkinje cell protein 4(Pcp4) | ||
| O88587 | Catechol-O-methyltransferase(Comt) | ||
| P48320 | Glutamic acid decarboxylase 2(Gad2) | ||
| P06837 | Growth associated protein 43(Gap43) | ||
| P42859 | Huntingtin(Htt) | ||
| P33173 | Kinesin family member 1A(Kif1a) | ||
| Q9CQV6 | Microtubule-associated protein 1 light chain 3 beta(Map1lc3b) | ||
| P10637 | Microtubule-associated protein tau(Mapt) | ||
| Q9JM52 | Misshapen-like kinase 1 (zebrafish)(Mink1) | ||
| P13595 | Neural cell adhesion molecule 1(Ncam1) | ||
| O35136 | Neural cell adhesion molecule 2(Ncam2) | ||
| Postsynaptic density | |||
| O35927 | Catenin (cadherin associated protein), delta 2(Ctnnd2) | ||
| Q9JLM8 | Doublecortin-like kinase 1(Dclk1) | ||
| Q9QXS6 | Drebrin 1(Dbn1) | ||
| P06837 | Growth associated protein 43(Gap43) | ||
| P42859 | Huntingtin(Htt) | ||
| P10637 | Microtubule-associated protein tau(Mapt) | ||
| Q9JM52 | Misshapen-like kinase 1 (zebrafish)(Mink1) | ||
| Q60875 | Rho/rac guanine nucleotide exchange factor (GEF) 2(Arhgef2) | ||
| Dendritic spine | |||
| Q5SSM3 | Rho GTPase activating protein 44(Arhgap44) | ||
| P47757 | Capping protein (actin filament) muscle Z-line, beta(Capzb) | ||
| O88587 | Catechol-O-methyltransferase(Comt) | ||
| Q9QXS6 | Ddrebrin 1(Dbn1) | ||
| P35802 | Glycoprotein m6a(Gpm6a) | ||
| P31324 | Protein kinase, cAMP dependent regulatory, type II beta(Prkar2b) | ||
| P62137 | Protein phosphatase 1, catalytic subunit, alpha isoform(Ppp1ca) | ||
| Growth cone | |||
| Q3UNH4 | G protein-regulated inducer of neurite outgrowth 1(Gprin1) | ||
| P97427 | Collapsin response mediator protein 1(Crmp1) | ||
| Q62188 | Dihydropyrimidinase-like 3(Dpysl3) | ||
| Q9QXS6 | Drebrin 1(Dbn1) | ||
| Q61553 | Fascin actin-bundling protein 1(Fscn1) | ||
| P10637 | Microtubule-associated protein tau(Mapt) | ||
| P13595 | Neural cell adhesion molecule 1(Ncam1) | ||
| Microtubule | |||
| Q9Z0H8 | CAP-GLY domain containing linker protein 2(Clip2) | ||
| P63168 | Dynein light chain LC8-type 1(Dynll1) | ||
| P33173 | Kinesin family member 1A(Kif1a) | ||
| P28738 | Kinesin family member 5 C(Kif5c) | ||
| Q9CQV6 | Microtubule-associated protein 1 light chain 3 beta(Map1lc3b) | ||
| P10637 | Microtubule-associated protein tau(Mapt) | ||
| Q60875 | Rho/rac guanine nucleotide exchange factor (GEF) 2(Arhgef2) | ||
| P68369 | Tubulin, alpha 1A(Tuba1a) | ||
| Q7TMM9 | Tubulin, beta 2A class IIA(Tubb2a) | ||
| MF | Microtubule binding | ||
| Q9Z0H8 | CAP-GLY domain containing linker protein 2(Clip2) | ||
| Q9EQF6 | Dihydropyrimidinase-like 5(Dpysl5) | ||
| P33173 | Kinesin family member 1A(Kif1a) | ||
| Q9CQV6 | Microtubule-associated protein 1 light chain 3 beta(Map1lc3b) | ||
| P10637 | Microtubule-associated protein tau(Mapt) | ||
| Q60875 | Rho/rac guanine nucleotide exchange factor (GEF) 2(Arhgef2) | ||
| Q9QY76 | Vesicle-associated membrane protein, associated protein B and C(Vapb) | ||
| Filamin binding | |||
| P97427 | Collapsin response mediator protein 1(Crmp1) | ||
| Q62188 | Dihydropyrimidinase-like 3(Dpysl3) | ||
| O35098 | Dihydropyrimidinase-like 4(Dpysl4) | ||
| Calmodulin binding | |||
| Q61656 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5(Ddx5) | ||
| Q61545 | Ewing sarcoma breakpoint region 1(Ewsr1) | ||
| P63054 | Purkinje cell protein 4(Pcp4) | ||
| P08414 | Calcium/calmodulin-dependent protein kinase IV(Camk4) | ||
| P06837 | Growth associated protein 43(Gap43) | ||
| Q61481 | Phosphodiesterase 1A, calmodulin-dependent(Pde1a) | ||
| Beta-tubulin binding | |||
| P47757 | Capping protein (actin filament) muscle Z-line, beta(Capzb) | ||
| P42859 | Huntingtin(Htt) | ||
| Q9QY76 | Vesicle-associated membrane protein, associated protein B and C(Vapb) |
BP, biological process; CC, cellular components; MF, molecular functions.