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. Author manuscript; available in PMC: 2019 Nov 4.
Published in final edited form as: Oral Oncol. 2018 Mar 14;80:9–15. doi: 10.1016/j.oraloncology.2018.02.021

Table 4.

Univariate analysis for composite carotid artery stenosis per carotid artery.

Factor (Reference) HR 95% CI p-value
Age (years, continuous) 1.02 0.999–1.04 0.07
Sex (F) 0.5 0.3–1.04 0.07
Smoking (No) 1.7 1.1–2.7 0.03*
HTN (No) 1.3 0.8–2.0 0.3
HLD (No) 1.6 1.03–2.6 0.04*
DM (No) 2.8 1.6–4.8 0.0003*
CAD (No) 2.4 1.4–4.2 0.002*
Heart Disease (No) 0.9 0.3–2.5 0.86
PAD (No) 3.6 1.1–11.6 0.03*
Neck dissection (No) 1.4 0.9–2.4 0.17
Chemotherapy (No) 0.9 0.5–1.6 0.73
RT Side: Contralateral 1.9 0.7–5.3 0.21
Entire carotid:
Max dose per 10Gy 1.001 0.999–1.002 0.41
Mean dose per 10Gy 1.00 0.999–1.002 0.56
V40 1.003 0.995–1.01 0.54
V50 1.002 0.9–1.1 0.96
V60 1.003 0.994–1.01 0.54
V70 1.04 0.9–1.2 0.45
Carotid bulb:
Max dose per 10Gy 1.001 0.999–1.002 0.36
Mean dose per 10Gy 1.00 0.999–1.002 0.49
V40 1.003 0.995–1.01 0.50
V50 1.006 0.9–1.1 0.85
V60 1.002 0.996–1.01 0.46
V70 1.03 0.97–1.1 0.39