Table 1.
Demographic And Clinical Characteristics Of The Patients With Mono-EBSI Or Mixed-EBSI
| Characteristics | Total (n=451) | Mono-EBSI (n =294) | Mixed-EBSI (n =157) | P-value |
|---|---|---|---|---|
| Age, median years (IQR) | 63.0(50.0,72.0) | 63.0(51.0,73.0) | 61.0(47.0,71.0) | 0.317 |
| Male sex | 320(71.0%) | 212(72.1%) | 108(68.8%) | 0.460 |
| Co-morbidities | ||||
| Diabetes mellitus | 73(16.2%) | 44(15.0%) | 29(18.0%) | 0.336 |
| Chronic kidney disease | 29(6.4%) | 20(6.8%) | 9(5.7%) | 0.659 |
| Chronic liver disease | 17(3.8%) | 11(3.7%) | 6(3.8%) | 0.966 |
| COPD or Severe asthma | 27(6.0%) | 19(6.5%) | 8(5.1%) | 0.560 |
| Chronic cardiac insufficiency | 38(8.4%) | 26(8.8%) | 12(7.6%) | 0.662 |
| Solid tumour | 105(23.3%) | 75(25.0%) | 30(19.1%) | 0.125 |
| Trauma | 88(19.5%) | 45(15.3%) | 43(27.4%) | 0.002 |
| Burn injury | 29(6.4%) | 7(2.4%) | 22(14.0%) | <0.001 |
| Cerebrovascular accident | 69(15.3%) | 45(15.3%) | 24(15.3%) | 0.996 |
| CCI, median (IQR) | 3(2,5) | 4(2,5) | 3(1,5) | 0.089 |
| APACHE II score, median (IQR) | 16(11.21) | 15(10.20) | 18(13.22) | 0.001 |
| SOFA score, median (IQR) | 5(4,9) | 5(3,8) | 6(4,9) | 0.005 |
| Pitt Bacteremia Score, median (IQR) | 4(2,6) | 3(1,5) | 4(3,6) | <0.001 |
| Hospitalization ward | ||||
| Medical | 41(9.1%) | 29(9.9%) | 12(7.6%) | 0.435 |
| Surgical | 132(29.0%) | 99(33.7%) | 33(21.0%) | 0.005 |
| ICU | 278(61.6%) | 166(56.5%) | 112(71.0%) | 0.002 |
| Previous treatment | ||||
| Hyperalimentation | 219(48.6%) | 135(45.9%) | 84(55.3%) | 0.125 |
| Mechanical ventilation | 309(68.5%) | 186(63.3%) | 123(78.3%) | 0.001 |
| Antibiotic exposure | 426(94.5%) | 279(94.9%) | 147(93.6%) | 0.575 |
| Surgery | 222(49.2%) | 139(47.3%) | 83(52.9%) | 0.258 |
| Chemotherapy/radiation | 11(2.4%) | 6(2.0%) | 5(3.2%) | 0.453 |
| Renal replacement therapy | 38(8.4%) | 25(8.5%) | 13(8.3%) | 0.935 |
| Blood transfusion | 49(10.9%) | 24(8.2%) | 25(15.9%) | 0.012 |
| Invasive devices | ||||
| Central line | 196(43.5%) | 117(39.8%) | 79(50.3%) | 0.032 |
| Indwelling urinary catheter | 321(71.2%) | 203(69.0%) | 118(75.2%) | 0.172 |
| Intraperitoneal drainage | 87(19.3%) | 58(19.7%) | 29(18.5%) | 0.747 |
| Prior hospital stay, median days (IQR) | 9.0(4.0.19.0) | 8.5(3.0.15.3) | 12.0(5.0.21.0) | 0.001 |
| Nosocomial infection | 396(87.8%) | 253(86.1%) | 143(91.1%) | 0.120 |
Notes: Bold indicates P<0.05.
Abbreviations: COPD, chronic obstructive pulmonary disorder; CCI, Charlson Comorbidity Index; ICU, intensive care unit; APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment; IQR, interquartile range; EBSI, enterococcal bloodstream infections.