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. 2019 Oct 31;12:8977–8989. doi: 10.2147/OTT.S218182

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© 2019 Lv et al.

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Effects of Bag-1 siRNA and cisplatin on the regulation of A549 cell apoptosis. A549 cells were grown and infected by Bag-1 or negative control siRNA for 48 hrs and then treated with 5 μg/mL cisplatin for 24 hrs and subjected to a flow cytometric apoptosis assay. (A) Representative results of the Annexin V-APC/PI staining of A549 cells. Q3-UL necrosis, Q3-UR late apoptosis, Q3-LR early apoptosis, and a Q3-LL viable cell. (B) The graph is quantified data of the assay. *p=0.007 vs the non-treatment group and ^#p=0.010 vs the negative control siRNA group.