Figure 5.

Effects of a single cocaine exposure on mGluR1 mRNA levels following 9 and 43 d. Bar graphs illustrate quantitative analysis of mGluR1 mRNA levels 8 d (white bar) and 42 d (dark bar) after a single exposure of cocaine in reward-related forebrain regions of C57BL/6N mice. Data are normalized to the respective saline control group (saline group: 100% = 0) and expressed as mean ± SEM. Statistical analysis is performed by regionwise two-way ANOVA followed by Fisher's PLSD test and Bonferroni's correction, n = 4–8/group, corrected p values: *p < 0.05, **p < 0.01, ***p < 0.001 versus controls. CPu, caudate–putamen.