Skip to main content
. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Environ Int. 2019 Aug 31;132:105124. doi: 10.1016/j.envint.2019.105124

Table 3.

Associations between dialkyl phosphate metabolite concentrations during pregnancy and cord blood thyroid hormone concentrations

Mean TSH Mean FT4
Dialkyl phosphates β (95% CI) p β (95% CI) p
Average concentrations during pregnancy
Total dialkyl phosphates
 Model 1 −0.07 (−0.17 to 0.03) 0.15 0.12 (−1.47 to 1.70) 0.88
 Model 2 −0.07 (−0.18 to 0.03) 0.16 0.27 (−1.37 to 1.91) 0.75
Dimethyl alkyl phosphates
 Model 1 −0.08 (−0.17 to 0.02) 0.13 0.04 (−1.48 to 1.56) 0.96
 Model 2 −0.07 (−0.17 to 0.03) 0.15 0.15 (−1.41 to 1.72) 0.85
Diethyl alkyl phosphates
 Model 1 −0.02 (−0.10 to 0.06) 0.64 0.28 (−1.00 to 1.56) 0.67
 Model 2 −0.03 (−0.11 to 0.05) 0.45 0.39 (−0.94 to 1.72) 0.56

Average dialkyl phosphate metabolite concentrations (nmol/g creatinine) were computed by the geometric mean of the three urine collection phases.

All dialkyl phosphate metabolite concentrations and TSH values were log transformed.

N= 472 for TSH and n=477 for FT4.

Model 1 was adjusted for gestational age at blood sampling.

Model 2 was additionally adjusted for maternal age, parity, smoking and ethnicity, and child sex.