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. 2019 Oct 17;7(1):e000650. doi: 10.1136/bmjdrc-2019-000650

Figure 2.

Figure 2

IL-1α deficiency prevented the onset of HFD-induced glucose intolerance and attenuated fasting plasma insulin and adiponectin levels. GTT and glucose AUC at 10 (A) and 15 (B) weeks of HFD. Fasting plasma levels of insulin (C) and adiponectin (D) after 8 weeks of HFD. Data are presented as mean±SE. Asterisks/Hash marks depict statistically significant differences. *p≤0.05; ***p≤0.001 to Loxp. #p≤0.05 ###p≤0.001 to chow (student’s t-test or two-way ANOVA). ANOVA, analysis of variance; AUC, area under curve; GTT, glucose tolerance test; HFD, high-fat diet; IL, interleukin; KO, knockout.