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The mRNA levels of IL-6 and TNFα in eWAT were lower in HFD-fed IL-1α KO compared with Loxp mice. The mRNA expression level of IL-1α, IL-1β, IL-6 and TNFα in eWAT (A) and liver (B) of Loxp and IL-1α KO mice-fed HFD for 16 weeks. Data are presented as mean±SE. Asterisks depict statistically significant differences. *p≤0.05; **p≤0.01 to Loxp (student’s t-test). ANOVA, analysis of variance; HFD, high-fat diet; IL, interleukin; KO. knockout; TG, triglyceride; TNF, tumor necrosis factor.
