Table 1.
Sensitivity and specificity for each VLE feature in predicting a histology subtype
| Histology | Wide crypts | Irregular surface | Isolated one gland | Multiple atypical glands | Complex glands | Combined atypical/complex glands |
| Normal | 10 (63%) 63%, 45% |
0 (0%) 0%, 83% |
7 (44%) 44%, 71% |
3 (19%) 19%, 52% |
0 (0%) 0%, 88% |
3 (19%) 19%, 48% |
| Carditis | 30 (56%) 56%, 43% |
4 (7%) 7.4%, 79% |
19 (35%) 35%, 73% |
24 (44%) 44%, 57% |
1 (2%) 2%, 82% |
25 (46%) 46%, 52% |
| Intestinal metaplasia | 16 (64%) 64%, 46% |
5 (20%) 20%, 87% |
7 (28%) 28%, 68% |
11 (44%) 44%, 56% |
0 (0%) 0%, 87% |
11 (44%) 44%, 52% |
| LGD | 1 (100%) 100%, 44% |
1 (100%) 100%,86% |
0 (0)% 0%, 69% |
1 (100%) 100%, 57% |
0 (0%) 0%, 89% |
1 (100%) 100%, 53% |
| HGD/IMCA | 5 (46%) 45%, 42% |
6 (55%) 55%, 90% |
1 (9%) 9%, 68% |
6 (55%) 55%, 61% |
7 (64%) 64%, 96% |
9 (82%) 81%, 57% |
| T1b | 0 (0%) 0%, 42% |
0 (0%) 0%, 85% |
0 (0%) 25%, 68% |
3 (100%) 100%, 58% |
3 (100%) 100%, 93% |
3 (100%) 100%, 54% |
| All dysplasia | 6 (40%) 40%, 41% |
7 (47%) 47%, 91% |
1 (7%) 7%, 65% |
10 (67%) 67%, 60% |
10 (67%) 67%, 99% |
13 (87%) 87%, 56% |
| Neoplasia: HGD/IMCA/T1b | 5 (36%) 36%, 40% |
6 (43%) 41%, 83% |
1 (7%) 7%, 66% |
9 (64%) 64%, 59% |
10 (71%) 71%, 99% |
12 (86%) 86%, 58% |
HGD, high-grade dysplasia; IMCA, intramucosal cancer; LGD, low-grade dysplasia.