Table 2.
Descriptive characteristics of patients with DFCs
| Year | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | P for trend | ||||||||
| Age (mean, SD) | 65.33±12.84 | 65.84±13.05 | 65.83±13.19 | 65.92±13.34 | 66.27±13.42 | 66.33±13.47 | 66.06±13.58 | 66.30±13.63 | |||||||||
| Age≥60 years | 15 305 (66.4) | 17 483 (67.1) | 18 352 (67.1) | 19 356 (67.4) | 20 431 (68.6) | 20 762 (69.2) | 20 713 (68.3) | 21 276 (69.1) | 0.003 | ||||||||
| Male gender (N, %) | 12 511 | (54.2) | 14 387 | (55.3) | 15 271 | (55.8) | 16 055 | (55.9) | 16 616 | (55.8) | 16 991 | (56.6) | 17 320 | (57.1) | 17 584 | (57.1) | <0.001 |
| Comorbidities (N, %) | |||||||||||||||||
| Hypertension | 15 873 | (68.8) | 18 232 | (70.0) | 19 494 | (71.2) | 20 409 | (71.0) | 21 673 | (72.8) | 21 874 | (72.9) | 22 076 | (72.8) | 22 476 | (73.0) | 0.001 |
| Dyslipidemia | 7960 | (34.5) | 9025 | (34.7) | 9781 | (35.7) | 10 570 | (36.8) | 11 371 | (38.2) | 11 593 | (38.6) | 12 419 | (40.9) | 13 067 | (42.5) | <0.001 |
| Diabetic nephropathy | 3286 | (14.2) | 3812 | (14.6) | 4118 | (15.1) | 4667 | (16.2) | 4963 | (16.7) | 5187 | (17.3) | 5157 | (17.0) | 5258 | (17.1) | 0.001 |
| End-stage renal disease | 1128 | (4.9) | 1435 | (5.5) | 1735 | (6.3) | 2103 | (7.3) | 2376 | (8.0) | 2421 | (8.1) | 2375 | (7.8) | 2382 | (7.7) | 0.008 |
| Diabetic retinopathy | 452 | (2.0) | 520 | (2.0) | 502 | (1.8) | 540 | (1.9) | 507 | (1.7) | 497 | (1.7) | 403 | (1.3) | 377 | (1.2) | 0.001 |
| Diabetic neuropathy | 1005 | (4.4) | 991 | (3.8) | 1035 | (3.8) | 1064 | (3.7) | 1045 | (3.5) | 1045 | (3.5) | 949 | (3.1) | 960 | (3.1) | <0.001 |
| Coronary heart disease | 1309 | (5.7) | 1492 | (5.7) | 1510 | (5.5) | 1551 | (5.4) | 1739 | (5.8) | 1669 | (5.6) | 1784 | (5.9) | 1728 | (5.6) | 0.667 |
| Heart failure | 740 | (3.2) | 824 | (3.2) | 920 | (3.4) | 1034 | (3.6) | 1065 | (3.6) | 1075 | (3.6) | 969 | (3.2) | 924 | (3.0) | 0.763 |
| Ischemic stroke | 397 | (1.7) | 493 | (1.9) | 457 | (1.7) | 490 | (1.7) | 495 | (1.7) | 462 | (1.5) | 450 | (1.5) | 417 | (1.4) | 0.003 |
| Hemorrhagic stroke | 21 | (0.1) | 36 | (0.1) | 35 | (0.1) | 44 | (0.2) | 31 | (0.1) | 49 | (0.2) | 29 | (0.1) | 31 | (0.1) | 0.740 |
| MACEs* | 2467 | (10.7) | 2845 | (10.9) | 2922 | (10.7) | 3119 | (10.9) | 3330 | (11.2) | 3255 | (10.9) | 3232 | (10.7) | 3100 | (10.1) | 0.250 |
*MACEs: including coronary heart disease, heart failure, ischemic stroke and hemorrhagic stroke.
DFC, diabetic foot complication; MACE, major adverse cardiac event; N, number of patients.