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. 2019 Nov 4;14(11):e0224626. doi: 10.1371/journal.pone.0224626

Table 2. Univariate and multivariate Cox proportional-hazards regression analysis for incident metabolic syndrome in the entire cohort and the propensity score-matched cohort.

Total cohort (n = 28,880) Matched cohort (n = 1,092)
Unadjusted Covariate-adjusted Unadjusted
HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value
NAFLD 8.60 (5.12–14.46) <0.01 2.10 (1.18–3.71) 0.01 3.56 (1.79–7.07) <0.01
Age 1.04 (1.03–1.04) <0.01 1.03 (1.02–1.04) <0.01 1.01 (0.97–1.05) 0.60
Male 2.50 (2.00–3.13) <0.01 1.39 (1.06–1.84) 0.02 0.81 (0.24–2.66) 0.73
Body mass index 1.56 (1.45–1.69) <0.01 1.40 (1.29–1.53) <0.01 1.04 (0.14–7.62) 0.97
Current smoking 2.20 (1.74–2.84) <0.01 1.60 (1.20–2.14) <0.01 1.29 (0.65–2.55) 0.47

Cox proportional-hazards regression analysis to identify predictors of incident metabolic syndrome at follow-up health evaluation.

, adjusted for NAFLD, age, male, body mass index, current smoking.

CI, confidence interval; HR, hazard ratio; NAFLD, non-alcoholic fatty liver disease.