Table 3. HPV E6 sequences of study isolates with their nucleotide substitutions and amino acid changes.
| S/N | Name | HPV Type | E6 Size | aE6 Nucleotide Substitutions | E6 Amino acid change |
|---|---|---|---|---|---|
| 1 | NGIb106-52 | HPV-52 | 102-548nt (447bp) | T404C; C506G | No mutation |
| 2 | NGIb128-31 | HPV-31 | 108-557nt (450bp) | C285T; A320T; G404A; A407G; C520T | H60Y; A138V |
| 3 | NGIb168-42 | HPV-42 | 114-566nt (453bp) | G284A; T310G; T311G | F66W |
| 4 | NGSk203-58 | HPV-58 | 110-559nt (450bp) | C187T; G245C; C307T; T322C; C367A; A398G | V46L; D86E; N97D |
| 5 | NGSk241-86 | HPV-86 | 1-447nt (447bp) | T63A; G71A; T372C; A449C | D21E; S24N |
| 6 | NGSk246-81 | HPV-81 | 102-566nt (465bp) | C269G; C391T | N56K; T97I |
| 7 | NGSk256-18 | HPV-18 | 105-581nt (477bp) | T251C; G266A; C287G; G374A; T485C; C491A; A548G; C549A | N129K |
| 8 | NGSk260-35 | HPV-35 | 110-559nt (450bp) | C131A; A295T | No mutation |
| 9 | NGSk266-6 | HPV-6 | 102-554nt (453bp) | A221T; C251G; A323C; A365T; C392T; G473A; C479T | H50Q |
| 10 | NGSk270-44 | HPV-44 | 105-557nt (453bp) | T129G; A180C; C183T; G215C; A218G; G220C; T221C; A268T; C269T; A275T; C312G; A345G; A349T; G363T; A380G; T386G; A387C; C396T; b; C416T; C470G; C482T; A494G; G495A; T524C; A548C; A556G | S9A; N26H; S39T; Y55F; L70V; N81D; Y82F; V87L; N94K; K95Q; D122E; D131N |
| 11 | NGSk271-74 | HPV-74 | 1-453nt (453bp) | G35C; A129T; A148G; C331T; T361G | S12T; N50D; L121V |
| 12 | NGSk274-18 | HPV-18 | 105-581nt (477bp) | C287G; A476G; T485C; C549A | No mutation |
| 13 | NGSk275-16 | HPV-16 | 83-559nt (477bp) | T109C; G132T; C143G; G145T; T286A; A289G; C335T; A403G | R17I; Q21D; H85Y |
| 14 | NGSk277-86 | HPV-86 | 1-447nt (447bp) | T63A; G71A | D21E; S24N |
| 15 | NGSk278-16 | HPV-16 | 83-559nt (477bp) | C88G; T109C; G132T; C143G; G145T; T286A; A289G; C335T; A403G | H2Q; R17I; Q21D; H85Y |
| 16 | NGSk280-16 | HPV-16 | 83-559nt (477bp) | T109C; G132T; C143G; G145T; T286A; A289G; C335T; A403G | R17I; Q21D; H85Y |
| 17 | NGSk282-43 | HPV-43 | 102-569nt (468bp) | A105T; T218G; A256G; T380A; C513T; A543C | T2S; K52R; S148R |
| 18 | NGSk291-16 | HPV-16 | 83-559nt (477bp) | T109C; G132T; C143G; G145T; T286A; A289G; C335T; A403G | R17I; Q21D; H85Y |
| 19 | NGSk294-66 | HPV-66 | 102-569nt (468bp) | T108C; C234T | S3P |
anucleotide substitutions in bolds translated into different amino acid respectively
bthe two highlighted nucleotide substitutions translated into only one amino acid change