Table 4. HPV E7 sequences of study isolates with their nucleotide substitutions and amino acid changes.
S/N | Name | HPV Type | E7 Size | E7 Nucleotidea Substitutions | E7 Amino acid change |
---|---|---|---|---|---|
1 | NGIb106-52 | HPV-52 | 553-626nt (74bp) | No substitution | No mutation |
2 | NGIb128-31 | HPV-31 | 560-657nt (98bp) | G580A; C646T | No mutation |
3 | NGIb168-42 | HPV-42 | 542-638nt (97bp) | C607T; A628G; G634A | No mutation |
4 | NGSk203-58 | HPV-58 | 574-657nt (84bp) | No substitution | No mutation |
5 | NGSk241-86 | HPV-86 | 423-478nt (56bp) | A449C | K9N |
6 | NGSk246-81 | HPV-81 | 542-628nt (87bp) | C616T; G625A; C626T | No mutation |
7 | NGSk256-18 | HPV-18 | 590-683nt (94bp) | C593T | H2Y |
8 | NGSk260-35 | HPV-35 | 562-644nt (83bp) | G595T | V12F |
9 | NGSk266-6 | HPV-6 | 530-632nt (103bp) | G617C; T618C; A619T | V30P |
10 | NGSk270-44 | HPV-44 | 533-619nt (87bp) | A548C; A556G; C572G; A580T | T6P; Q14E; E16D |
11 | NGSk271-74 | HPV-74 | 429-526nt (98bp) Insertion of CCT |
Insertion of b at A512CCT513G | Insertion of at L28P29D |
12 | NGSk274-18 | HPV-18 | 590-620nt (31bp) | T612C | L8S |
13 | NGSk275-16 | HPV-16 | 562-646nt (85bp) | A646G | No mutation |
14 | NGSk277-86 | HPV-86 | 423-507nt (85bp) | No substitution | No mutation |
15 | NGSk278-16 | HPV-16 | 562-648nt (87bp) | A646G; T648C | N29D |
16 | NGSk280-16 | HPV-16 | 562-646nt (85bp) | A646G | No mutation |
17 | NGSk282-43 | HPV-43 | 530-614nt (85bp) | A543C | K5T |
18 | NGSk291-16 | HPV-16 | 562-646nt (85bp) | A646G | No mutation |
19 | NGSk294-66 | HPV-66 | 572-659nt (88bp) | A586T; G628T; G658A | No mutation |
anucleotide substitutions in bolds translated into different amino acid respectively
binsertion of CCT (highlighted) translated to Proline (P)