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. 2019 Nov 4;14(11):e0224073. doi: 10.1371/journal.pone.0224073

Fig 2. Skin induration.

Fig 2

Induration was defined as the mean of the length and width in millimeters, measure on days 1, 2, 3, and every 7 days after each injection until resolution or the end of the study. (A-C) Induration measurements at S1, S2, and S3, respectively. The first (d0), second (d14) and third (d28) doses were administered at S1, S2, and S3, respectively. Data is shown as the kinetics of mean induration/group (n = 5-7/group/dose). Arrows indicate days of immunization. (D) Individual peak induration measured from each site. Grey squares and white circles represent individual measurements of mice injected with mLT and dmLT, respectively, while bars represent the mean of each group. *P<0.05.