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. 2019 Oct 23;15(10):e1008117. doi: 10.1371/journal.ppat.1008117

Table 3. Titration of the PMSA-adapted recombinant samples inoculated into TgVole (1x).

Inoculum Dilution Model Survival time of positive animals
(dpi) (mean±SEM)
Attack ratea
L-seeded-PMSA (1) 10−1 TgVole 266±3 10/10 (100%)
L-seeded-PMSA (1) 10−2 TgVole 281±6 4/4 (100%)
L-seeded-PMSA (1) 10−4 TgVole 321±6 5/5 (100%)
L-seeded-PMSA (1) 10−5 TgVole 434±21 2/5 (40%)

a Data obtained based on neurological clinical signs and protease-resistant PrP detection.

SEM: Standard Error of Mean. dpi: day post inoculation.