Table 2.
Quality of Life assessment
| Median [IQR] | P value (< 0.05) | ||
|---|---|---|---|
| Week 0 | Week 19 | ||
| PedsQL TM 4.0 Generic Core Scales | |||
| Self-report | |||
| Physical performance | 87.50 [37.50;96.88] | 85.94 [64.06;93.75] | 0.854 |
| Psychosocial health | 85.00 [73.33;86.67] | 87.50 [76.67;93.33] | 0.273 |
| Total score | 82.61 [60.87;86.96] | 84.78 [74.46;93.48] | 0.715 |
| Parent report | |||
| Physical performance | 78.13 [28.13;90.63] | 82.81 [62.50;86.72] | 0.715 |
| Psychosocial health | 44.57 [42.39;54.35] | 48.91 [46.47;49.73] | 0.144 |
| Total score | 44.57 [42.39;54.35] | 48.91 [46.47;49.73] | 0.144 |
| PedsQL TM Multidimensional Fatigue Scale | |||
| Self-report | |||
| General score | 75.00 [58.33;89.58] | 83.33 [75.00;91.67] | 0.713 |
| Sleep score | 79.17 [56.25;97.92] | 83.33 [70.83;93.75] | 0.414 |
| Cognitive fatigue score | 79.17 [66.67;100.00] | 83.33 [62.50;97.92] | 0.713 |
| Total score | 81.94 [61.81;88.19] | 81.94 [73.61;90.97] | 0.500 |
| Parent report | |||
| General score | 66.67 [50.00;77.08] | 87.50 [68.75;93.75] | 0.273 |
| Sleep score | 83.33 [54.17;93.75] | 83.33 [83.33;95.83] | 0.461 |
| Cognitive fatigue score | 75.00 [56.25;89.58] | 95.83 [77.08;97.92] | 0.141 |
| Total score | 81.94 [54.86;84.72] | 86.11 [81.11;92.36] | 0.080 |
| PedsQL TM 3.0 Cancer Module | |||
| Self-report | |||
| Pain | 100.00 [68.75;100.00] | 100.00 [75.00;100.00] | 0.276 |
| Nausea | 85.00 [60.00;97.50] | 80.00 [60.00;90.00] | 1.000 |
| Fear of procedures | 83.33 [25.00;100.00] | 16.67 [4.17;50.00] | 0.131 |
| Fear of treatment | 100.00 [62.50;100.00] | 75.00 [54.17;100.00] | 0.414 |
| Worry | 100.00 [66.67;100.00] | 83.33 [75.00;100.00] | 0.655 |
| Cognitive functioning | 80.00 [62.50;100.00] | 75.00 [50.00;100.00] | 0.197 |
| Appearance | 100.00 [75.00;100.00] | 100.00 [87.50;100.00] | 0.785 |
| Communication | 83.33 [70.83;100.00] | 83.33 [70.83;100.00] | 0.157 |
| Total score | 77.78 [75.93;90.28] | 77.78 [69.44;80.56] | 0.080 |
| Parent report | |||
| Pain | 87.50 [68.75;100.00] | 100.00 [87.50;100.00] | 1.000 |
| Nausea | 90.00 [62.50;97.50] | 65.00 [40.00;85.00] | 0.223 |
| Fear of procedures | 75.00 [25.00;100.00] | 25.00 [00.00;58.33] | 0.109 |
| Fear of treatment | 75.00 [45.83;100.00] | 75.00 [54.17;100.00] | 0.655 |
| Worry | 91.67 [62.50;100.00] | 75.00 [75.00;100.00] | 0.854 |
| Cognitive functioning | 65.00 [44.38;75.00] | 60.00 [55.63;75.00] | 0.892 |
| Appearance | 83.33 [66.67;100.00] | 83.33 [75.00;95.83] | 0.577 |
| Communication | 83.33 [54.17;100.00] | 100.00 [87.50;100.00] | 0.564 |
| Total score | 78.85 [64.35;86.22] | 72.22 [68.32;81.02] | 0.080 |