. Author manuscript; available in PMC: 2019 Nov 4.

Published in final edited form as: Diabetes Care. 2018 Oct 23;42(2):208–214. doi: 10.2337/dc18-0431

Table 3.

Hazard ratios from Cox proportional regression model (adjusted for cohort) for time to insulin censored at 5 years (30 SNP T1D GRS).

Variable	Hazard Ratio (95% CI)	p value
GADA negative	1
GADA positive	3.43 (2.50, 4.71)	<0.001
GADA negative:T1D GRS (per 1 SD increase in T1D GRS)	1.02 (0.94, 1.12)	>0.1
GADA positive:T1D GRS (per 1 SD increase in T1D GRS)	1.48 (1.15, 1.90)	0.002
Age at diagnosis (per 1 year)	0.97 (0.96, 0.97)	<0.001
BMI (per kg/m² unit)^*	1.00 (0.98, 1.01)	>0.1

Closest to diagnosis