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. Author manuscript; available in PMC: 2019 Nov 4.
Published in final edited form as: Diabetes Care. 2018 Oct 23;42(2):208–214. doi: 10.2337/dc18-0431

Table 3.

Hazard ratios from Cox proportional regression model (adjusted for cohort) for time to insulin censored at 5 years (30 SNP T1D GRS).

Variable Hazard Ratio (95% CI) p value
GADA negative 1
GADA positive 3.43 (2.50, 4.71) <0.001
GADA negative:T1D GRS (per 1 SD increase in T1D GRS) 1.02 (0.94, 1.12) >0.1
GADA positive:T1D GRS (per 1 SD increase in T1D GRS) 1.48 (1.15, 1.90) 0.002
Age at diagnosis (per 1 year) 0.97 (0.96, 0.97) <0.001
BMI (per kg/m2 unit)* 1.00 (0.98, 1.01) >0.1
*

Closest to diagnosis