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Box 1 Pharmacokinetic data oral vs injection
| Oral flupentixol dihydrochloride (Depixol®) | Intramuscular flupentixol decanoate (Depixol®) | |
|---|---|---|
| Licensed dose range | 3–9 mg twice daily | 50 mg every 4 weeks to 400 mg every week |
| Bioavailability | 40–55% | 100% |
| Time to peak levels | 4 h | 4–7 days |
| Mean plasma half-life (SD) | 35 h | 17 days (9.2) |
| Time to steady state | 7 days | 2–3 months |
