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. 2019 Oct 29;10:2417. doi: 10.3389/fmicb.2019.02417

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Copyright © 2019 Rizvi, Shankar, Chatterjee, More, Bose, Dutta, Balakrishnan, Madugulla, Rapole, Mande, Banerjee and Mande.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic pathway impact analysis revealing the significantly impacted metabolic pathways under (A) acidic, (B) oxidative, (C) iron deprivation, and (D) nutrient starvation stresses compared to the control. Each dot represents a unique metabolic pathway, with dot color corresponding to the –log(P) value and size of the dot corresponding to the pathway impact score. The same metabolic pathways across the four pairwise comparisons are represented by same letters. 1: Alanine, aspartate and glutamate metabolism, 2: Arginine and proline metabolism, 3: Citrate cycle (TCA cycle), 4: Cysteine and methionine metabolism, 5: Glycine, serine and threonine metabolism, 6: Nicotinate and nicotinamide metabolism, 7: Purine metabolism, 8: Pyrimidine metabolism, 9: Pyruvate metabolism, 10: D-Glutamine and D-glutamate metabolism. Detailed pairwise pathway impact is provided in Supplementary Table S6.