Figure 3.

BER of damaged DNA within various chromatin environments. The indicated substrates (10 nM; Fig. 1) were incubated with UDG and APE1 (1 nM each) in the presence of either 0.2 mM Mg²⁺ (a,b) or 2.0 mM Mg²⁺ (c,d). Error bars represent standard deviation from at least three independent experiments. See Table 1 for relevant statistics.