Table 3.

Multivariate analyses of factors associated with recurrence-free survival and overall survival

	Hazard ratio (95% CI)	P
RFS
Tumor size, cm (≥5 vs. <5)	2.530 (1.355–4.725)	0.004
ASPP2 (high vs. low)	0.505 (0.257–0.989)	0.026
HMGCR (high vs. low)	2.182 (1.147–4.150)	0.017
OS
Tumor size, cm (≥5 vs. <5)	2.103 (1.122–3.942)	0.02
ASPP2 (high vs. low)	0.453 (0.235–0.873)	0.017
HMGCR (high vs. low)	2.530 (1.355–4.725)	0.004

Multivariate analysis, cox proportional hazards regression model

Variables were adopted for their prognostic significance by univariate analysis and no obvious correlation between each other