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. 2019 Oct 29;10:1216. doi: 10.3389/fphar.2019.01216

Figure 5.

Figure 5

DCX immunohistochemical analysis of the effects of OS extract in improving scopolamine-induced suppression of neurogenesis in the dentate gyrus. (A) DCX-positive staining in immature neurons is shown in the SGZ of the dentate gyrus. Photomicrographs of the hippocampal section of treatment groups was (i) Control (ii) SCP 1 mg/kg alone (iii) DPZ 1 mg/kg + SCP 1 mg/kg (iv) 50 mg/kg OS + SCP 1 mg/kg (v) 100 mg/kg + SCP 1 mg/kg (vi) 200 mg/kg + SCP 1 mg/kg. Representative photomicrographs were taken at magnifications of 40× and 200×. (B) Quantification of DCX population. Data are expressed as means Mean ± SEM, n = 4 – 6 and statistical analysis by one-way ANOVA followed by Dunnett test **P < 0.01, ***P < 0.001 and ****P < 0.0001.