Table 1.
Karyotypes of 157 women with Turner syndrome treated (GH+) or not treated with growth hormone in childhood (GH−), as revealed in their medical histories. V – absolute values, (%) – percent.
| Karyotype | GH+(n = 33) | GH−(n = 124) | GH+ vs GH− | ||
|---|---|---|---|---|---|
| V | (%) | V | (%) | P - value | |
| Simple X monosomy (45,X) | 20 | 60.6 | 72 | 58.1 | 0.7955 |
| Structural abnormalities of the X chromosome (e.g. isochromosome X, partial deletion of an arm of the X chromosome, ring X chromosome or translocation between the X chromosome and the autosomal material) | 5 | 15.1 | 12 | 9.7 | 0.3751 |
| Mosaic karyotypes | 8 | 24.3 | 40 | 32.2 | 0.3812 |
| a. X monosomy and normal female cell line | 3 | 9.1 | 13 | 10.5 | 0.8134 |
| b. X monosomy and normal male cell line | 2 | 6.1 | 5 | 4 | 0.6028 |
| c. X monosomy and a second aneuploid cell line (trisomy) | 1 | 3 | 1 | 0.8 | 0.3144 |
| d. X monosomy and a second cell line with structural chromosome abnormality | 2 | 6.1 | 21 | 16.9 | 0.1187 |
| Sum | 33 | 100 | 124 | 100 | |