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. 2019 Nov 4;9:15951. doi: 10.1038/s41598-019-52332-0

Table 2.

Clinical and laboratory characteristics of 157 women with Turner syndrome (TS) treated (GH+) or not treated with growth hormone in childhood (GH−). Shown are the mean ± SD, ranges are shown in brackets, and normal ranges are shown in square brackets for laboratory investigations.

Parameters [normal ranges] GH +
(n = 33)
GH−
(n = 124)
GH + vs GH−
P - value
Age years 21.8 ± 3.49 (18–31) 26.2 ± 7.9 (18–53) 0.016
Height cm 148.3 ± 6.57 (136–161.5) 143.4 ± 6.15 (123–167.5) 0.0001
Weight kg 47.7 ± 7.84 (37.1–70.8) 50.1 ± 9.7 (34–76.1) 0.2
BMI kg/m2 21.7 ± 3.7 (16.8–34.4) 24.4 ± 4.4 (16.8–38.1) 0.0019
Age at final TS diagnosis y. 10.1 ± 5 (1–25) 15.3 ± 8.1 (1–44) 0.0008
FSH IU/L [2.8–11.3] 50.2 ± 26.7 (0.5–132) 34 ± 20.6 (0.5–60) 0.0021
FSH > 40 IU/L % 63.6 40.3 0.017
LH (IU/L) [1.1–77] 27.2 ± 17.7 (1–93) 22.5 ± 16.4 (1–81) 0.2
E2 (pmol/L) [66–884] 152.6 ± 161 (45.9–598) 106.6 ± 119 (36.7–838.2) 0.0649
E2 < 110 pmol/L % 39.4 28.2 0.2
Cholesterol mmol/L [3.9–5] 4.6 ± 0.88 (3–6.6) 5.1 ± 1.04 (2.8–10.7) 0.0256
HDL mmol/L [ > 0.91] 1.34 ± 0.37 (0.8–2.3) 1.5 ± 0.48 (0.5–3) 0.1
LDL mmol/L [ < 3.88] 3 ± 0.79 (1.5–4.9) 3.3 ± 0.9 (1.4–7.1) 0.049
TG g/L [0.4–1.5] 0.9 ± 0.47 (0.2–2.9) 1.1 ± 0.62 (0.4–4) 0.046
Glucose mmol/L [3.9–5.6] 5.1 ± 0.67 (3.7–6.4) 5.1 ± 0.89 (3.2–10.6) 0.85
Creatinine µmol/L [60–130] 62 ± 10.4 (41.9–81.4) 59.8 ± 14.7 (33.8–161) 0.4
Protein g/L [60–80] 73.9 ± 6.8 (53.5–82.5) 73.6 ± 4.9 (60–86) 0.7
Hematocrit % [40–50] 44 ± 2.6 (39.6–50) 44.2 ± 3.6 (33.9–59) 0.7
Hemoglobin g/dL [12–16] 14.2 ± 0.9 (12.2–16.3) 14.3 ± 0.9 (11.6–17) 0.7
Red blood cells 1012/L [4.2–5] 4.66 ± 0.3 (4.2–5.2) 4.72 ± 0.5 (3.3–6.2) 0.4
White blood cells 109/L [4–8] 6.5 ± 1.4 (3.2–9.3) 7.1 ± 2 (3.6–13.9) 0.1085
Thrombocytes 109/L [150–300] 228.6 ± 56.2 (114–329) 259.3 ± 72.5 (113–485) 0.0249