Table 4.
The somatic anomalies and clinical features in 157 women with Turner syndrome treated (GH+) or not treated with growth hormone in childhood (GH−), as revealed by physical examination. V – absolute values, (%) – percent.
| Parameter | GH + (n = 33) | GH− (n = 124) | GH + vs GH− P - value | ||
|---|---|---|---|---|---|
| V | (%) | V | (%) | ||
| Pigmented nevi | 33 | 100 | 122 | 98.4 | 0.5 |
| Hypertrichosis on the face | 4 | 12.2 | 7 | 5.6 | 0.2 |
| Low-set and/or deformed ears | 29 | 87.9 | 103 | 83.1 | 0.5 |
| Dental caries and lost teeth | 1 | 3 | 8 | 6.5 | 0.4 |
| High-arched palate | 29 | 87.9 | 110 | 88.7 | 0.9 |
| Malocclusion | 17 | 51.5 | 57 | 46 | 0.6 |
| Retrognathism | 26 | 78.8 | 71 | 57.3 | 0.024 |
| Oral cavity soft tissue abnormalities | 2 | 6.1 | 3 | 2.4 | 0.3 |
| Drooping eyelids | 13 | 39.4 | 64 | 51.2 | 0.2 |
| Epicanthal folds | 12 | 36.4 | 43 | 34.7 | 0.9 |
| Dense eyebrows, long eyelashes | 14 | 42.4 | 92 | 74.2 | 0.0005 |
| Squint | 5 | 15.2 | 17 | 13.7 | 0.8 |
| Daltonism | 0 | 0 | 2 | 1.6 | 0.5 |
| Low hairline on the nuchae | 21 | 63.6 | 70 | 56.5 | 0.5 |
| Neck anomalies (short, webbed) | 13 | 39.4 | 73 | 58.9 | 0.046 |
| Posture defects | 16 | 48.5 | 53 | 42.7 | 0.6 |
| Finger deformity | 9 | 27.3 | 32 | 25.8 | 0.9 |
| Fingernail anomalies | 22 | 66.7 | 59 | 47.5 | 0.0498 |
| Blood pressure ≥ 140/90 mmHg | 4 | 12.2 | 36 | 29 | 0.049 |