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. 2019 Nov 4;9:15940. doi: 10.1038/s41598-019-52367-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Katanin p60 haploinsufficiency does not affect long-term potentiation at the dentate gyrus. (A) Long-term potentiation (LTP) at the medial perforant pathway following a high-frequency stimulation protocol. (B) Both genotypes showed similar synaptic potentiation based on the mean EPSP slope during the last 5 min of recordings. Insets show analogue traces of EPSPs recorded during baseline and 30 min after high-frequency stimulation. Scale bars: 2 mV/2 ms. (C) There were no significant EPSP slope differences in basal conditions between genotypes. (D,E) Sholl analysis of dentate gyrus granule cells show no significant differences in dendritic arborization between genotypes.