Table 1.

Susceptibility and resistance rates (%) of antibiotics against Cutibacterium acnes

Antibiotics	Breakpoints (μg/ml)		Number	%R	%I	%S	MIC50 (μg/ml)	MIC90 (μg/ml)	MIC range (μg/ml)
	S	R
Ampicillin	≤ 0.5	≥ 2	63	0	0	100	≤ 0.06	0.25	0.06 to 0.25
Ampicillin/sulbactam	≤ 8	≥ 32	63	0	0	100	≤ 0.06	0.125	0.06 to 0.25
Ceftriaxone	≤ 16	≥ 64	63	0	0	100	≤ 0.06	0.125	0.06 to 0.25
Cefoxitin	≤ 16	≥ 64	63	0	0	100	0.25	0.5	0.125 to 2
Imipenem	≤ 4	≥ 16	63	0	0	100	≤ 0.06	≤ 0.06	0.06 to 0.06
Moxifloxacin	≤ 0.5	≥ 2	63	4.8	0	95.2	0.25	≤ 0.25	0.06 to 2
Clindamycin	≤ 2	≥ 8	63	28.6	12.7	58.7	0.5	> 128	0.06 to > 128
Erythromycin	≤ 0.5	≥ 8	63	49.2	0	50.8	> 128	> 128	0.06 to > 128
Fusidic acid	≤ 1	≥ 4	63	0	6.3	93.7	0.5	1	0.25 to 2
Minocycline	≤ 4	≥ 16	63	0	0	100	≤ 0.06	0.125	0.06 to 1
Tetracycline	≤ 4	≥ 16	63	0	0	100	0.25	0.25	0.125 to 1
Metronidazole	≤ 8	≥ 32	63	100	0	0	> 128	> 128	> 128 to > 128

R resistance, I intermediate, S susceptibility