Table 2.
Association between specific leukocyte infiltration as measured by mED and measures of adiposity in the LEAP study sample.
| BMI* | AFM* | |||||||
|---|---|---|---|---|---|---|---|---|
| Cell Type | Effect | 95% CI | LRTP | R2 | Effect | 95% CI | LRTP | R2 |
| ActivatedNK | −1.047 | (−1.635, −0.458) | 4.9E-04 | 0.080 | −0.801 | (−1.448, −0.154) | 0.014 | 0.036 |
| Monocyte | −0.961 | (−1.536, −0.387) | 0.001 | 0.073 | −1.091 | (−1.698, −0.484) | 4.3E-04 | 0.115 |
| NK | −0.942 | (−1.526, −0.359) | 0.001 | 0.068 | −0.500 | (−1.145, 0.145) | 0.122 | 0.017 |
| CD4 | −0.834 | (−1.464, −0.203) | 0.009 | 0.047 | −0.753 | (−1.396, −0.11) | 0.020 | 0.054 |
| Immature B | 0.828 | (0.108, 1.548) | 0.022 | 0.032 | 0.763 | (0.015, 1.512) | 0.042 | 0.023 |
| Granulocyte | −0.299 | (−0.588, −0.011) | 0.039 | 0.029 | −0.065 | (−0.366, 0.236) | 0.665 | 0.001 |
| Treg | −0.255 | (−0.757, 0.247) | 0.310 | 0.007 | 0.378 | (−0.171, 0.927) | 0.169 | 0.014 |
| Memory B | −0.247 | (−0.859, 0.365) | 0.420 | 0.004 | 0.627 | (−0.074, 1.329) | 0.075 | 0.031 |
| Plasma B | 0.235 | (−0.36, 0.83) | 0.430 | 0.004 | 0.957 | (0.31, 1.604) | 0.004 | 0.047 |
| Naïve B | −0.184 | (−0.763, 0.395) | 0.526 | 0.003 | 0.717 | (0.061, 1.372) | 0.030 | 0.036 |
| CD8 | −0.182 | (−0.813, 0.448) | 0.562 | 0.003 | 0.204 | (−0.452, 0.859) | 0.534 | 3.3E-07 |
| Dendritic | −0.168 | (−0.76, 0.425) | 0.571 | 0.003 | −0.767 | (−1.373, −0.162) | 0.012 | 0.066 |
*
Adjusted for age, sex, race, current smoking (cig/day); BMI: body mass index; AFM: android fat mass (kg); CI: confidence interval; LRTP: likelihood ratio test p-value; R2: marginal R-squared value