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. 2019 Jul 24;4(10):1401–1411. doi: 10.1016/j.ekir.2019.07.009

Figure 3.

Figure 3

Best 3-marker interdisease signature to distinguish chronic kidney disease (CKD) of uncertain etiology (CKDu) from CKD. (a) Receiver operating characteristic analysis of 3-marker combination panel OPN+KIM1+RBP4 in distinguishing CKDu from nonendemic chronic kidney disease (NECKD) and endemic chronic kidney disease (ECKD) are shown along with the performance of individual protein markers. Area under the curve (AUC) reported based on the validation set. (b) Performance of serum creatinine in distinguishing CKDu from NECKD is shown. KIM1, kidney injury molecule-1; OPN, osteopontin; RBP4, retinol binding protein 4.