Table 1.

Top 20 upregulated genes in drug relapsed PDX tumors.

Ranking	Gene Symbol	Gene Name	BL0293_FC	BL0440_FC
1	MAGEA11	Melanoma-Associated Antigen 11	2.75	8.50
2	MAT1A	Methionine Adenosyltransferase 1A	6.66	3.40
3	DIO2	Iodothyronine Deiodinase 2	3.04	6.72
4	PWWP2B	PWWP Domain-Containing Protein 2B	4.91	3.67
5	PAGE2	Prostate-Associated Gene 2 Protein	4.68	2.67
6	FAM133A	Family With Sequence Similarity 133 Member A	4.25	2.81
7	ABHD17C	Abhydrolase Domain Containing 17C	2.37	4.53
8	LINC00839	Long Intergenic Non-Protein Coding RNA 839	2.75	3.62
9	OAS1	2′-5′-Oligoadenylate Synthetase 1	1.63	4.56
10	RSAD2	Radical S-Adenosyl Methionine Domain Containing 2	2.49	3.28
11	CMPK2	Cytidine/Uridine Monophosphate Kinase 2	1.80	3.67
12	HMGN5	High Mobility Group Nucleosome Binding Domain 5	2.80	2.49
13	ZNF300P1	Zinc Finger Protein 300 Pseudogene 1	2.64	1.91
14	SEPT14	Septin 14	1.75	2.57
15	CEBPA	CCAAT Enhancer Binding Protein Alpha	2.09	1.81
16	KCNC4	Potassium Voltage-Gated Channel Subfamily C Member 4	1.66	2.19
17	NNMT	Nicotinamide N-Methyltransferase	1.52	2.23
18	MPC1	Mitochondrial Pyruvate Carrier 1	1.69	1.71
19	ZNF385B	Zinc Finger Protein 385B	1.70	1.52
20	CEBPD	CCAAT Enhancer Binding Protein Delta	1.57	1.60