Table 1.

Netlog method performance of five-fold cross validation and independent test.

Cross Validation.	Size	Combined-Instance				Homolog-Instance				Target-Instance
		PR	SE		MCC	PR	SE		MCC	PR	SE		MCC
Positive class	55,862	0.8653	0.9154		0.7957	0.8641	0.8944		0.7786	0.8617	0.9112		0.7864
Negative class	55,862	0.9098	0.8568		0.7934	0.8896	0.8582		0.7767	0.9018	0.8480		0.7823
[Acc; MCC; ROC-AUC]		[88.62%; 0.7935; 0.9420]				[87.64%; 0.7773; 0.9396]				[87.64%; 0.7773; 0.9459]
F1 Score		0.8897				0.8790				0.8858
Independent test		Positive class *						Negative class *
		IntAct		Reactome		HitPredict		Experimental		Random		Neglog
		90.20%		79.14%		86.76%		53.00%		71.38%		96.40%

* denotes recall or recognition rate.