Figure 2.

WECS augments whole-body energy metabolism. After 6 weeks of HFD and 7 weeks of treatment, WECS upregulated oxygen consumption (A). However, WECS has no effect on energy intake in mice (B) and activity (C). WECS treatment increased the thermal infrared signal (D) and rectal temperature (E) after cold stimulation of mice. PET-CT results show that WECS increased the BAT activity in mice (F). The bar graph represents the average uptake of 18F-FDG in BAT (G). Bars represent the mean + SEM, n = 3–5. * p < 0.05 compared with HFD control.