Figure 8.

WECS modulates the composition of the gut microbiota. Microbiota composition in feces of HFD mice treated with or without 1% WECS and LFD mice were analyzed using next-generation sequencing (n = 7 for each group). NMDS and Multivar/One-way ANOSIM analysis were used to explore the similarity between groups (A). Results of the bacterial taxonomic profiling at the phylum level of intestinal bacteria from different mouse groups (B–E). The heatmap shows that the abundance of 85 OTUs was significantly altered in HFD-fed mice (F). We also screened several representative microbes associated with obesity (G–K). Bars represent the mean + SEM, n = 6–7. * p < 0.05, **p < 0.01, ***p < 0.01 compared with the HFD control.