Figure 7.
Analysis of TNFSF13b and SOCS2 expression in osteoblasts. Forced miR-29a expression (A) attenuated the glucocorticoid-provoked TNFSF13b expression in osteoblasts, whereas loss of miR-29a function increased the cytokine expression (B). SOCS2 knockdown (C) attenuated the glucocorticoid-mediated increases in TNFSF13b expression (D). Data are expressed as the mean ± standard errors calculated from 3 experiments. Asterisks * indicate significant differences from the scramble group and hashtags # indicate significant differences from the GC group. GC, glucocorticoid; miR-29a-AS, miR-29a antisense oligonucleotide; RNAi, RNA interference.