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Canagliflozin at a concentration of 10 μM attenuated cell proliferation of HepG2 cells and induce cell cycle arrest. (a) Real-time analysis of cell proliferation of HepG2 cells in a dose-dependent manner. (b) Treatment with 10 μM canagliflozin inhibited HepG2 cell proliferation when compared with the control or 100 nM canagliflozin. (c) Canagliflozin inhibits G2/M cell cycle progression of HepG2 cells.
