Figure 7.

Leptin induce invasion in MCF10A cells in a Src-dependent manner. (A) Representative light microscopy images of invasion assays of MCF10A cells pre-treated with AraC and grown in the presence or absence of leptin, and the Src inhibitor PP2. (B) Quantitative analyses of the invasion assays presented in (A); the values represent the mean ± SD of three independent experiments, and are expressed as a cell invasion ratio (between invading and non-invading cells). The asterisks indicate the comparison made with respect to the control. *** p < 0.001 by a one-way ANOVA (Newman-Keuls’s test).