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. 2019 Sep 24;8(10):1140. doi: 10.3390/cells8101140

Figure 2.

Figure 2

miRNAs involved in NK cell development, NK cell activation, and tumor immunity. (A) miRNAs involved in mouse and human NK cell development and maturation. miRNAs listed with arrows regulate each developmental transition of NK cells. Note that human NK cell development, unlike mouse NK cell development, lacks a CILP stage. (B) miRNAs involved in IFN-γ production, NK cell cytotoxic capacity, and immune escape in human and mouse systems, respectively. CLP, common lymphoid progenitor; CILP, common innate lymphoid progenitor; NKP, NK-cell precursor; iNK, immature NK; NK, natural killer cell.