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. 2019 Oct 1;8(10):1185. doi: 10.3390/cells8101185

Figure 2.

Figure 2

Inhibitors of oxidative phosphorylation increase Ptgs2 mRNA stability. (A) Western blot analysis of c-Jun N-terminal kinase (JNK), IκB kinase (IKK), and p38 mitogen-activated protein kinase (MAPK) phosphorylation in astrocytes treated for 0.5 hours with IL-1α in the presence or absence of rotenone, oligomycin, and antimycin, as indicated. (B) The mRNA expression of Ptgs2 in astrocytes treated with IL-1α, antimycin, and oligomycin for 1 hour followed by actinomycin D for indicated times. Note: *, p < 0.05 vs. IL-1α. Data represent mean values ± SE of 3 or 4 independent experiments.