Table 2.
Differentially expressed genes (DEGs) contributing to flavonoid biosynthesis in the young shoots and expanding true leaves of ttg1-13 plants at 20 days after germination. DEGs with |log2 ratios| ≥ 1.00, and only GO Slim IDs with FDR ≤ 0.05, are listed here.
| Differentially Expressed Genes | log2 Ratios | Functions | References |
|---|---|---|---|
| MYC2 (AT1G32640) | −1.27 | Promoting flavonoid accumulation | [50,51,52,53] |
| GL2 (AT1G79840) | −6.33 | Inhibiting anthocyanin accumulation | [66] |
| TTG2 (AT2G37260) | −7.89 | Promoting flavonoid accumulation | [25,57] |
| ANL2 (AT4G00730) | −1.06 | Promoting anthocyanin accumulation | [67] |
| TT8 (AT4G09820) | −7.14 | Promoting flavonoid accumulation | [68,69] |
| PAL4 (AT3G10340) | −3.72 | Converting phenylalanine into trans-cinnamic acid | [70,71] |
| F3’H (AT5G07990) | −4.08 | Converting naringenin and dihydrokaempferol into eriodictyol and dihydroquercetin, respectively | [70,72] |
| DMR6 (AT5G24530) | −9.50 | Converting flavanones into flavones | [73] |
| FLS3 (AT5G63590) | −7.55 | Promoting flavonol accumulation | [74] |
| DFR (AT5G42800) | −10.85 | Converting dihydroflavonols into leucoanthocyanidins | [2,75] |
| ANS (AT4G22880) | −10.68 | Converting leucoanthocyanidins into 3-OH-anthocyanins | [76,77] |
| UGT79B1 (AT5G54060) | −8.29 | Involved in the glycosylation of anthocyanins | [70,78] |
| UGT75C1 (AT4G14090) | −4.09 | Involved in the malonylation of anthocyanins | [79] |
| 5MAT (AT3G29590) | −11.05 | Involved in the accumulation of malonylated anthocyanins | [80] |
| GSTF12 (AT5G17220) | −3.73 | Involved in transport and accumulation of both anthocyanins and proanthocyanidins | [81,82] |